If you had a preterm birth, you are at risk for early delivery again, EVERY WEEK COUNTS
Watch Kate's video

Meet Kate. Her previous preterm birth put her at risk for another one. Hear her story.

After consultation with her doctor, Kate made a decision to start Makena® (hydroxyprogesterone caproate injection) because she was at risk for another preterm birth. Hear her story

Kate gave birth to her son, Gabriel, 5 weeks early (35 weeks). When she became pregnant again a year later, she learned she was at risk for another preterm birth and discussed Makena with her healthcare provider.

Watch Heather's video

Meet Heather. She and her healthcare provider chose an FDA-approved product to help lower her chance of having another preterm birth. Hear her story.

Hear why Heather and her healthcare provider chose an FDA-approved product in her fight against recurrent preterm birth

After giving birth to her daughter Astrid 5 weeks early, Heather's doctor told her she was at risk for another preterm birth. Heather and her healthcare provider talked about Makena® (hydroxyprogesterone caproate injection) as a treatment option to help give her second baby a better chance to have more time to develop.

Watch Lyn's video

Meet Lyn. Because she delivered her son early, she was at risk for another preterm birth. Hear her story.

Lyn was surprised to find out she was at risk for another preterm birth due to her history, so she decided to take action

After her older son, Lamar, was born 4 weeks early and spent 19 days in the NICU, Lyn wanted to understand what she could do to help improve her chance of achieving a full-term pregnancy with her second child.

Watch Katie's video

Meet Katie. She wanted to do what she could to help reduce her risk of delivering another baby too soon. Hear her story.

Understand why receiving FDA-approved Makena® (hydroxyprogesterone caproate injection) was important to Katie

When Katie's water broke unexpectedly at 34 weeks with her first child, she wasn't prepared. Katie wanted to do what she could to help reduce her risk of delivering another baby too soon.

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Indication

Makena (hydroxyprogesterone caproate injection) is a prescription hormone medicine (progestin) used to lower the risk of preterm birth in women who are pregnant with one baby and who have delivered one baby too early (preterm) in the past. Makena was shown to work based on a lower number of women who delivered babies at less than 37 weeks of pregnancy. There are no studies showing Makena reduces the number of babies who have serious problems shortly after birth or who die. It is not known whether Makena is safe and effective in women who have other risk factors for preterm birth.

Important safety information for Makena (hydroxyprogesterone caproate injection)

Makena should not be used in women with any of the following conditions: blood clots or other blood clotting problems, breast cancer or other hormone-sensitive cancers, or history of these conditions; unusual vaginal bleeding not related to your current pregnancy, yellowing of the skin due to liver problems during pregnancy, liver problems, including liver tumors, or uncontrolled high blood pressure.

Before you receive Makena, tell your healthcare provider if you have an allergy to hydroxyprogesterone caproate, castor oil, or any of the other ingredients in Makena; diabetes or prediabetes, epilepsy, migraine headaches, asthma, heart problems, kidney problems, depression, or high blood pressure.

In a clinical study, certain complications or events associated with pregnancy occurred more often in women who received Makena. These included miscarriage (pregnancy loss before 20 weeks of pregnancy), stillbirth (fetal death occurring during or after the 20th week of pregnancy), hospital admission for preterm labor, preeclampsia (high blood pressure and too much protein in your urine), gestational hypertension (high blood pressure caused by pregnancy), gestational diabetes, and oligohydramnios (low amniotic fluid levels).

Makena may cause serious side effects including blood clots, allergic reactions, depression, and yellowing of your skin and the whites of your eyes. Call your healthcare provider right away if you think you have symptoms of a blood clot (leg swelling, redness in your leg, a spot on your leg that is warm to touch, or leg pain that worsens when you bend your foot) or symptoms of an allergic reaction (hives, itching, or swelling of the face). The most common side effects of Makena include injection site reactions (pain, swelling, itching, bruising, or a hard bump), hives, itching, nausea, and diarrhea.

You are encouraged to report negative side effects of prescription drugs to the FDA.

Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please see full Makena prescribing information.

Important safety information and Indication
INDICATION
IMPORTANT SAFETY INFORMATION
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